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Sequestosome‐1 (p62) expression reveals chaperone‐assisted selective autophagy in immune‐mediated necrotizing myopathies

Diffuse myofiber necrosis in the context of inflammatory myopathy is the hallmark of immune‐mediated necrotizing myopathy (IMNM). We have previously shown that skeletal muscle fibers of IMNM patients may display nonrimmed vacuoles and sarcoplasmic irregularities. The dysfunctional chaperone activity...

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Detalles Bibliográficos
Autores principales: Fischer, Norina, Preuße, Corinna, Radke, Josefine, Pehl, Debora, Allenbach, Yves, Schneider, Udo, Feist, Eugen, von Casteleyn, Vincent, Hahn, Katrin, Ruck, Tobias, Meuth, Sven G., Goebel, Hans‐Hilmar, Graf, Rose, Mammen, Andrew, Benveniste, Olivier, Stenzel, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018061/
https://www.ncbi.nlm.nih.gov/pubmed/31376301
http://dx.doi.org/10.1111/bpa.12772