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RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies

Loss of function mutations within the vesicular trafficking protein Ras analogy in brain 39B (RAB39B) are associated with rare X‐linked Parkinson’s disease (PD). Physiologically, RAB39B is localized to Golgi vesicles and recycling endosomes and is required for glutamatergic receptor maturation but a...

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Detalles Bibliográficos
Autores principales: Koss, David J., Bondarevaite, Odeta, Adams, Sara, Leite, Marta, Giorgini, Flaviano, Attems, Johannes, Outeiro, Tiago F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018064/
https://www.ncbi.nlm.nih.gov/pubmed/32762091
http://dx.doi.org/10.1111/bpa.12890