PKR kinase directly regulates tau expression and Alzheimer's disease‐related tau phosphorylation

Deposition of extensively hyperphosphorylated tau in specific brain cells is a clear pathological hallmark in Alzheimer's disease and a number of other neurodegenerative disorders, collectively termed the tauopathies. Furthermore, hyperphosphorylation of tau prevents it from fulfilling its phys...

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Detalles Bibliográficos
Autores principales: Reimer, Lasse, Betzer, Cristine, Kofoed, Rikke Hahn, Volbracht, Christiane, Fog, Karina, Kurhade, Chaitanya, Nilsson, Emma, Överby, Anna K., Jensen, Poul Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018097/
https://www.ncbi.nlm.nih.gov/pubmed/32716602
http://dx.doi.org/10.1111/bpa.12883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018097/
https://www.ncbi.nlm.nih.gov/pubmed/32716602
http://dx.doi.org/10.1111/bpa.12883

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