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Ependymoma relapse goes along with a relatively stable epigenome, but a severely altered tumor morphology

The molecular biology of ependymomas is not well understood and this is particularly true for ependymoma relapses. We aimed at finding out if and to which extent, relapses differ from their corresponding primary tumors on the morphological, chromosomal and epigenetic level. We investigated 24 matche...

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Detalles Bibliográficos
Autores principales: Yang, Denise, Holsten, Till, Börnigen, Daniela, Frank, Stephan, Mawrin, Christian, Glatzel, Markus, Schüller, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018105/
https://www.ncbi.nlm.nih.gov/pubmed/32633004
http://dx.doi.org/10.1111/bpa.12875