Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

The megakaryocyte/erythroid transient myeloproliferative disorder (TMD) in newborns with Down syndrome (DS) occurs when Nterminal truncating mutations of the hemopoietic transcription factor GATA1, that produce GATA1short protein (GATA1s), are acquired early in development. Prior work has shown that...

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Detalles Bibliográficos
Autores principales: Juban, Gaëtan, Sakakini, Nathalie, Chagraoui, Hedia, Hernandez, David Cruz, Cheng, Qian, Soady, Kelly, Stoilova, Bilyana, Garnett, Catherine, Waithe, Dominic, Otto, Georg, Doondeea, Jessica, Usukhbayar, Batchimeg, Karkoulia, Elena, Alexiou, Maria, Strouboulis, John, Morrissey, Edward, Roberts, Irene, Porcher, Catherine, Vyas, Paresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018159/
https://www.ncbi.nlm.nih.gov/pubmed/32527952
http://dx.doi.org/10.3324/haematol.2019.244541

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018159/
https://www.ncbi.nlm.nih.gov/pubmed/32527952
http://dx.doi.org/10.3324/haematol.2019.244541

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