Cyclovirobuxine D Induces Apoptosis and Mitochondrial Damage in Glioblastoma Cells Through ROS-Mediated Mitochondrial Translocation of Cofilin

BACKGROUND: Cyclovirobuxine D (CVBD), a steroidal alkaloid, has multiple pharmacological activities, including anti-cancer activity. However, the anti-cancer effect of CVBD on glioblastoma (GBM) has seldom been investigated. This study explores the activity of CVBD in inducing apoptosis of GBM cells...

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Detalles Bibliográficos
Autores principales: Zhang, Lin, Fu, Ruoqiu, Duan, Dongyu, Li, Ziwei, Li, Bin, Ming, Yue, Li, Li, Ni, Rui, Chen, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018288/
https://www.ncbi.nlm.nih.gov/pubmed/33816313
http://dx.doi.org/10.3389/fonc.2021.656184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018288/
https://www.ncbi.nlm.nih.gov/pubmed/33816313
http://dx.doi.org/10.3389/fonc.2021.656184

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