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Cyclovirobuxine D Induces Apoptosis and Mitochondrial Damage in Glioblastoma Cells Through ROS-Mediated Mitochondrial Translocation of Cofilin

BACKGROUND: Cyclovirobuxine D (CVBD), a steroidal alkaloid, has multiple pharmacological activities, including anti-cancer activity. However, the anti-cancer effect of CVBD on glioblastoma (GBM) has seldom been investigated. This study explores the activity of CVBD in inducing apoptosis of GBM cells...

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Detalles Bibliográficos
Autores principales:	Zhang, Lin, Fu, Ruoqiu, Duan, Dongyu, Li, Ziwei, Li, Bin, Ming, Yue, Li, Li, Ni, Rui, Chen, Jianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018288/ https://www.ncbi.nlm.nih.gov/pubmed/33816313 http://dx.doi.org/10.3389/fonc.2021.656184

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