Polarclean/Water as a Safe and Recoverable Medium for Selective C2-Arylation of Indoles Catalyzed by Pd/C

[Image: see text] Herein, we report the use of nontoxic, water-miscible Polarclean as a safe dipolar aprotic solvent for the metal-catalyzed direct C2–H arylation of indoles using Pd/C as a catalyst. The developed method allows reaching excellent yields and regioselectivities, and it tolerates vario...

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Detalles Bibliográficos
Autores principales: Campana, Filippo, Massaccesi, Beatrice Maria, Santoro, Stefano, Piermatti, Oriana, Vaccaro, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018292/
https://www.ncbi.nlm.nih.gov/pubmed/33828930
http://dx.doi.org/10.1021/acssuschemeng.0c05049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018292/
https://www.ncbi.nlm.nih.gov/pubmed/33828930
http://dx.doi.org/10.1021/acssuschemeng.0c05049

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