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Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling

Background: Recent evidence indicates that host-gut microbiota crosstalk has nonnegligible effects on host skeletal muscle, yet gut microbiota-regulating mechanisms remain obscure. Methods: C57BL/6 mice were treated with a cocktail of antibiotics (Abx) to depress gut microbiota for 4 weeks. The prof...

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Detalles Bibliográficos
Autores principales: Qiu, Yixuan, Yu, Jiaming, Li, Yi, Yang, Fan, Yu, Huiyuan, Xue, Mengjuan, Zhang, Fan, Jiang, Xin, Ji, Xueying, Bao, Zhijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018554/
https://www.ncbi.nlm.nih.gov/pubmed/33783283
http://dx.doi.org/10.1080/07853890.2021.1900593