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Metformin Strongly Affects Gut Microbiome Composition in High-Fat Diet-Induced Type 2 Diabetes Mouse Model of Both Sexes

Effects of metformin, the first-line drug for type 2 diabetes therapy, on gut microbiome composition in type 2 diabetes have been described in various studies both in human subjects and animals. However, the details of the molecular mechanisms of metformin action have not been fully understood. More...

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Detalles Bibliográficos
Autores principales: Silamiķele, Laila, Silamiķelis, Ivars, Ustinova, Monta, Kalniņa, Zane, Elbere, Ilze, Petrovska, Ramona, Kalniņa, Ineta, Kloviņš, Jānis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018580/
https://www.ncbi.nlm.nih.gov/pubmed/33815284
http://dx.doi.org/10.3389/fendo.2021.626359