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Overexpressed Tumor Suppressor Exosomal miR-15a-5p in Cancer Cells Inhibits PD1 Expression in CD8+T Cells and Suppresses the Hepatocellular Carcinoma Progression

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common primary liver tumor, and the main reason is the unclear pathogenesis of HCC, which leads to a high fatality rate of HCC. Therefore, it is of great clinical significance to explore the molecular mechanism of HCC and find a targeted therape...

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Detalles Bibliográficos
Autores principales: Zhang, Hong-Yu, Liang, Hong-Xia, Wu, Shu-Huan, Jiang, He-Qing, Wang, Qin, Yu, Zu-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018596/
https://www.ncbi.nlm.nih.gov/pubmed/33816255
http://dx.doi.org/10.3389/fonc.2021.622263