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BRCA1–BARD1 Regulates Axon Regeneration in Concert with the Gqα–DAG Signaling Network

The breast cancer susceptibility protein BRCA1 and its partner BRCA1-associated RING domain protein 1 (BARD1) form an E3-ubiquitin (Ub) ligase complex that acts as a tumor suppressor in mitotic cells. However, the roles of BRCA1–BARD1 in postmitotic cells, such as neurons, remain poorly defined. Her...

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Detalles Bibliográficos
Autores principales: Sakai, Yoshiki, Hanafusa, Hiroshi, Shimizu, Tatsuhiro, Pastuhov, Strahil I., Hisamoto, Naoki, Matsumoto, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018897/
https://www.ncbi.nlm.nih.gov/pubmed/33593852
http://dx.doi.org/10.1523/JNEUROSCI.1806-20.2021