Cargando…
BRCA1–BARD1 Regulates Axon Regeneration in Concert with the Gqα–DAG Signaling Network
The breast cancer susceptibility protein BRCA1 and its partner BRCA1-associated RING domain protein 1 (BARD1) form an E3-ubiquitin (Ub) ligase complex that acts as a tumor suppressor in mitotic cells. However, the roles of BRCA1–BARD1 in postmitotic cells, such as neurons, remain poorly defined. Her...
Autores principales: | Sakai, Yoshiki, Hanafusa, Hiroshi, Shimizu, Tatsuhiro, Pastuhov, Strahil I., Hisamoto, Naoki, Matsumoto, Kunihiro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018897/ https://www.ncbi.nlm.nih.gov/pubmed/33593852 http://dx.doi.org/10.1523/JNEUROSCI.1806-20.2021 |
Ejemplares similares
-
TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor
por: Sakai, Yoshiki, et al.
Publicado: (2019) -
Caenorhabditis elegans F-Box Protein Promotes Axon Regeneration by Inducing Degradation of the Mad Transcription Factor
por: Shimizu, Tatsuhiro, et al.
Publicado: (2021) -
The Integrin Signaling Network Promotes Axon Regeneration via the Src–Ephexin–RhoA GTPase Signaling Axis
por: Sakai, Yoshiki, et al.
Publicado: (2021) -
Phosphatidylserine exposure mediated by ABC transporter activates the integrin signaling pathway promoting axon regeneration
por: Hisamoto, Naoki, et al.
Publicado: (2018) -
Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling
por: Pastuhov, Strahil Iv., et al.
Publicado: (2012)