Metformin prevents stroke damage in non-diabetic female mice with chronic kidney disease

Chronic kidney disease (CKD) worsens ischemic stroke severity in both patients and animals. In mice, these poorer functional outcomes are associated with decreased brain activity of AMP-activated protein kinase (AMPK), a molecule that recently emerged as a potential therapeutic target for ischemic s...

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Detalles Bibliográficos
Autores principales: Grissi, Maria, Boudot, Cédric, Assem, Maryam, Candellier, Alexandre, Lando, Mathilde, Poirot-Leclercq, Sabrina, Boullier, Agnès, Bennis, Youssef, Lenglet, Gaëlle, Avondo, Carine, Lalau, Jean-Daniel, Choukroun, Gabriel, Massy, Ziad A., Kamel, Saïd, Chillon, Jean-Marc, Hénaut, Lucie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018962/
https://www.ncbi.nlm.nih.gov/pubmed/33811249
http://dx.doi.org/10.1038/s41598-021-86905-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018962/
https://www.ncbi.nlm.nih.gov/pubmed/33811249
http://dx.doi.org/10.1038/s41598-021-86905-9

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