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Effectiveness of decontamination protocols when analyzing ancient DNA preserved in dental calculus

Ancient DNA analysis of human oral microbial communities within calcified dental plaque (calculus) has revealed key insights into human health, paleodemography, and cultural behaviors. However, contamination imposes a major concern for paleomicrobiological samples due to their low endogenous DNA con...

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Detalles Bibliográficos
Autores principales: Farrer, Andrew G., Wright, Sterling L., Skelly, Emily, Eisenhofer, Raphael, Dobney, Keith, Weyrich, Laura S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8018977/
https://www.ncbi.nlm.nih.gov/pubmed/33811235
http://dx.doi.org/10.1038/s41598-021-86100-w