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Spesolimab, an Anti-Interleukin-36 Receptor Antibody, in Patients with Palmoplantar Pustulosis: Results of a Phase IIa, Multicenter, Double-Blind, Randomized, Placebo-Controlled Pilot Study

INTRODUCTION: Palmoplantar pustulosis (PPP) is a chronic, inflammatory skin disease, with high disease burden, that is often refractory to treatment. There is a high unmet clinical need for the treatment of patients with PPP. The objectives of this study were to evaluate the safety and efficacy of s...

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Detalles Bibliográficos
Autores principales: Mrowietz, Ulrich, Burden, A. David, Pinter, Andreas, Reich, Kristian, Schäkel, Knut, Baum, Patrick, Datsenko, Yakov, Deng, Hongjie, Padula, Steven J., Thoma, Christian, Bissonnette, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019016/
https://www.ncbi.nlm.nih.gov/pubmed/33661508
http://dx.doi.org/10.1007/s13555-021-00504-0