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POST1/C12ORF49 regulates the SREBP pathway by promoting site-1 protease maturation

Sterol-regulatory element binding proteins (SREBPs) are the key transcriptional regulators of lipid metabolism. The activation of SREBP requires translocation of the SREBP precursor from the endoplasmic reticulum to the Golgi, where it is sequentially cleaved by site-1 protease (S1P) and site-2 prot...

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Detalles Bibliográficos
Autores principales: Xiao, Jian, Xiong, Yanni, Yang, Liu-Ting, Wang, Ju-Qiong, Zhou, Zi-Mu, Dong, Le-Wei, Shi, Xiong-Jie, Zhao, Xiaolu, Luo, Jie, Song, Bao-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019017/
https://www.ncbi.nlm.nih.gov/pubmed/32666500
http://dx.doi.org/10.1007/s13238-020-00753-3