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Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF‐1α regulator

We previously reported that ROR1 is a crucial downstream gene for the TTF‐1/NKX2‐1 lineage‐survival oncogene in lung adenocarcinoma, while others have found altered expression of ROR1 in multiple cancer types. Accumulated evidence therefore indicates ROR1 as an attractive molecular target, though it...

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Detalles Bibliográficos
Autores principales: Isomura, Hisanori, Taguchi, Ayumu, Kajino, Taisuke, Asai, Naoya, Nakatochi, Masahiro, Kato, Seiichi, Suzuki, Keiko, Yanagisawa, Kiyoshi, Suzuki, Motoshi, Fujishita, Teruaki, Yamaguchi, Tomoya, Takahashi, Masahide, Takahashi, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019194/
https://www.ncbi.nlm.nih.gov/pubmed/33506575
http://dx.doi.org/10.1111/cas.14825