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The noncanonical role of EZH2 in cancer

Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of polycomb repressive complex 2 (PRC2). Dysregulation of EZH2 causes alteration of gene expression and functions, thereby promoting cancer development. The regulatory function of EZH2 varies across different tumor types. The canonical role...

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Detalles Bibliográficos
Autores principales: Huang, Jinhua, Gou, Hongwei, Yao, Jia, Yi, Kaining, Jin, Zhigang, Matsuoka, Masao, Zhao, Tiejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019201/
https://www.ncbi.nlm.nih.gov/pubmed/33615636
http://dx.doi.org/10.1111/cas.14840