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Anti‐tumor efficacy of human anti‐c‐met CAR‐T cells against papillary renal cell carcinoma in an orthotopic model

Chimeric antigen receptor (CAR)‐T cell therapy has shown salient efficacy in cancer immunotherapy, particularly in the treatment of B cell malignancies. However, the efficacy of CAR‐T for solid tumors remains inadequate. In this study, we displayed that c‐met is an appropriate therapeutic target for...

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Detalles Bibliográficos
Autores principales: Mori, Jun‐ich, Adachi, Keishi, Sakoda, Yukimi, Sasaki, Takahiro, Goto, Shunsuke, Matsumoto, Hiroaki, Nagashima, Yoji, Matsuyama, Hideyasu, Tamada, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019206/
https://www.ncbi.nlm.nih.gov/pubmed/33539630
http://dx.doi.org/10.1111/cas.14835