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UHRF1 Induces Methylation of the TXNIP Promoter and Down-Regulates Gene Expression in Cervical Cancer

DNA methylation, and consequent down-regulation, of tumour suppressor genes occurs in response to epigenetic stimuli during cancer development. Similarly, human oncoviruses, including human papillomavirus (HPV), up-regulate and augment DNA methyltransferase (DNMT) and histone deacetylase (HDAC) acti...

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Detalles Bibliográficos
Autores principales: Kim, Min Jun, Lee, Han Ju, Choi, Mee Young, Kang, Sang Soo, Kim, Yoon Sook, Shin, Jeong Kyu, Choi, Wan Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019600/
https://www.ncbi.nlm.nih.gov/pubmed/33795533
http://dx.doi.org/10.14348/molcells.2021.0001