Cargando…

UHRF1 Induces Methylation of the TXNIP Promoter and Down-Regulates Gene Expression in Cervical Cancer

DNA methylation, and consequent down-regulation, of tumour suppressor genes occurs in response to epigenetic stimuli during cancer development. Similarly, human oncoviruses, including human papillomavirus (HPV), up-regulate and augment DNA methyltransferase (DNMT) and histone deacetylase (HDAC) acti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Min Jun, Lee, Han Ju, Choi, Mee Young, Kang, Sang Soo, Kim, Yoon Sook, Shin, Jeong Kyu, Choi, Wan Sung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019600/ https://www.ncbi.nlm.nih.gov/pubmed/33795533 http://dx.doi.org/10.14348/molcells.2021.0001

Ejemplares similares

Metformin inhibits cervical cancer cell proliferation via decreased AMPK O-GlcNAcylation
por: Kim, Min Young, et al.
Publicado: (2019)

O-GlcNAcylation of NF-κB Promotes Lung Metastasis of Cervical Cancer Cells via Upregulation of CXCR4 Expression
por: Ali, Akhtar, et al.
Publicado: (2017)

Methylation of UHRF1 by SET7 is essential for DNA double-strand break repair
por: Hahm, Ja Young, et al.
Publicado: (2019)

Methylated-UHRF1 and PARP1 interaction is critical for homologous recombination
por: Hahm, Ja Young, et al.
Publicado: (2020)

TXNIP Suppresses the Osteochondrogenic Switch of Vascular Smooth Muscle Cells in Atherosclerosis
por: Woo, Sang-Ho, et al.
Publicado: (2022)

Oxidative stress-mediated TXNIP loss causes RPE dysfunction
por: Ji Cho, Min, et al.
Publicado: (2019)

Ethanol down regulates the expression of myelin proteolipid protein in the rat hippocampus
por: Lee, Dong Hoon, et al.
Publicado: (2010)

Comparative biochemical analysis of UHRF proteins reveals molecular mechanisms that uncouple UHRF2 from DNA methylation maintenance
por: Vaughan, Robert M, et al.
Publicado: (2018)

O-linked N-acetylglucosamine transferase enhances secretory clusterin expression via liver X receptors and sterol response element binding protein regulation in cervical cancer
por: Kim, Min Jun, et al.
Publicado: (2017)

O-linked N-acetylglucosamine transferase promotes cervical cancer tumorigenesis through human papillomaviruses E6 and E7 oncogenes
por: Kim, Minjun, et al.
Publicado: (2016)

The Growing Complexity of UHRF1-Mediated Maintenance DNA Methylation
por: Xie, Si, et al.
Publicado: (2018)

TXNIP Deficiency Exacerbates Endotoxic Shock via the Induction of Excessive Nitric Oxide Synthesis
por: Park, Young-Jun, et al.
Publicado: (2013)

TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-γ Production during Bacterial Infection
por: Kim, Dong Oh, et al.
Publicado: (2020)

TXNIP regulates AKT‐mediated cellular senescence by direct interaction under glucose‐mediated metabolic stress
por: Huy, Hangsak, et al.
Publicado: (2018)

Tumor necrosis factor induces rapid down-regulation of TXNIP in human T cells
por: Levring, Trine B., et al.
Publicado: (2019)

Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells
por: Seo, Jung Seon, et al.
Publicado: (2017)

Association of UHRF1 with H3K9 methylation directs the maintenance of DNA methylation
por: Rothbart, Scott B., et al.
Publicado: (2012)

Role of UHRF1 in de novo DNA methylation in oocytes and maintenance methylation in preimplantation embryos
por: Maenohara, Shoji, et al.
Publicado: (2017)

Involvement of PGC7 and UHRF1 in the regulation of DNA methylation of the IG-DMR in the imprinted Dlk1-Dio3 locus : PGC7 and UHRF1 regulats IG-DMR methylation
por: Yu, Mengying, et al.
Publicado: (2022)

Downregulation of UHRF1 increases tumor malignancy by activating the CXCR4/AKT-JNK/IL-6/Snail signaling axis in hepatocellular carcinoma cells
por: Kim, Ji-Hyun, et al.
Publicado: (2017)

SET8 prevents excessive DNA methylation by methylation-mediated degradation of UHRF1 and DNMT1
por: Zhang, Huifang, et al.
Publicado: (2019)

A dummy-run evaluation of postoperative hypofractionated intensity-modulated radiation therapy (POHIM-RT) trials for cervical cancer
por: Cho, Won Kyung, et al.
Publicado: (2020)

A Longitudinal Study of BDNF Promoter Methylation and Depression in Breast Cancer
por: Kang, Hee-Ju, et al.
Publicado: (2015)

N-Lobe of TXNIP Is Critical in the Allosteric Regulation of NLRP3 via TXNIP Binding
por: Cheng, Fengyu, et al.
Publicado: (2022)

Alcohol dysregulates miR-148a in hepatocytes through FoxO1, facilitating pyroptosis via TXNIP overexpression
por: Heo, Mi Jeong, et al.
Publicado: (2019)

Non-Contiguous Spinal Injury in Cervical Spinal Trauma: Evaluation with Cervical Spine MRI
por: Choi, Soo-Jung, et al.
Publicado: (2004)

H3K9 methyltransferase G9a negatively regulates UHRF1 transcription during leukemia cell differentiation
por: Kim, Kee-Beom, et al.
Publicado: (2015)

DNA methylation and gene expression of TXNIP in adult offspring of women with diabetes in pregnancy
por: Houshmand-Oeregaard, Azadeh, et al.
Publicado: (2017)

Ethanol Augments Monosodium Urate-Induced NLRP3 Inflammasome Activation via Regulation of AhR and TXNIP in Human Macrophages
por: Kim, Seong-Kyu, et al.
Publicado: (2020)

Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation
por: Li, Tao, et al.
Publicado: (2018)

Resveratrol Inhibits Neuronal Apoptosis and Elevated Ca(2+)/Calmodulin-Dependent Protein Kinase II Activity in Diabetic Mouse Retina
por: Kim, Young-Hee, et al.
Publicado: (2010)

Functional dissection of the role of UHRF1 in the regulation of retinoblastoma methylome
por: Kan, Guangyan, et al.
Publicado: (2017)

Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1
por: Harrison, Joseph S, et al.
Publicado: (2016)

Cervical Spinal Epidural Hematoma Following Cervical Posterior Laminoforaminotomy
por: Choi, Jeong Hoon, et al.
Publicado: (2013)

Signaling Pathway of Taurine-Induced Upregulation of TXNIP
por: Satsu, Hideo, et al.
Publicado: (2022)

UHRF1 Induces Metastasis in Thyroid Cancer
por: Kuang, Bo-Hua, et al.
Publicado: (2022)

The UHRF protein family in epigenetics, development, and carcinogenesis
por: UNOKI, Motoko, et al.
Publicado: (2022)

ODP251 Thioredoxin-Interacting Protein (Txnip) And Cellular Senescence: Potential Adverse Effects of Txnip Deficiency.
por: Abubaker, Mohammed, et al.
Publicado: (2022)

Regulation of UHRF1 acetylation by TIP60 is important for colon cancer cell proliferation
por: Hong, Ye Joo, et al.
Publicado: (2022)

Upregulation of UHRF1 promotes the progression of melanoma by inducing cell proliferation
por: Wei, Chuanyuan, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_l88suhj28sstu5f50g58j38dvr