IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer

The oncofetal IGF2 mRNA-binding protein 1 (IGF2BP1) promotes tumor progression in a variety of solid tumors and its expression is associated with adverse prognosis. The main role proposed for IGF2BP1 in cancer cells is the stabilization of mRNAs encoding pro-oncogenic factors. Several IGF2BP1-RNA as...

Descripción completa

Detalles Bibliográficos
Autores principales: Glaß, Markus, Misiak, Danny, Bley, Nadine, Müller, Simon, Hagemann, Sven, Busch, Bianca, Rausch, Alexander, Hüttelmaier, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019740/
https://www.ncbi.nlm.nih.gov/pubmed/33829040
http://dx.doi.org/10.3389/fmolb.2021.632219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019740/
https://www.ncbi.nlm.nih.gov/pubmed/33829040
http://dx.doi.org/10.3389/fmolb.2021.632219

Ejemplares similares