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Gut-Derived Metabolite Indole-3-Propionic Acid Modulates Mitochondrial Function in Cardiomyocytes and Alters Cardiac Function

Background: The gut microbiome has been linked to the onset of cardiometabolic diseases, in part facilitated through gut microbiota-dependent metabolites such as trimethylamine-N-oxide. However, molecular pathways associated to heart failure mediated by microbial metabolites remain largely elusive....

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Detalles Bibliográficos
Autores principales: Gesper, Maren, Nonnast, Alena B. H., Kumowski, Nina, Stoehr, Robert, Schuett, Katharina, Marx, Nikolaus, Kappel, Ben A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019752/
https://www.ncbi.nlm.nih.gov/pubmed/33829028
http://dx.doi.org/10.3389/fmed.2021.648259