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Gut-Derived Metabolite Indole-3-Propionic Acid Modulates Mitochondrial Function in Cardiomyocytes and Alters Cardiac Function
Background: The gut microbiome has been linked to the onset of cardiometabolic diseases, in part facilitated through gut microbiota-dependent metabolites such as trimethylamine-N-oxide. However, molecular pathways associated to heart failure mediated by microbial metabolites remain largely elusive....
Autores principales: | Gesper, Maren, Nonnast, Alena B. H., Kumowski, Nina, Stoehr, Robert, Schuett, Katharina, Marx, Nikolaus, Kappel, Ben A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019752/ https://www.ncbi.nlm.nih.gov/pubmed/33829028 http://dx.doi.org/10.3389/fmed.2021.648259 |
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