A Requirement of Protein Geranylgeranylation for Chemokine Receptor Signaling and Th17 Cell Function in an Animal Model of Multiple Sclerosis

Precisely controlled lymphocyte migration is critically required for immune surveillance and successful immune responses. Lymphocyte migration is strictly regulated by chemokines and chemokine receptors. Here we show that protein geranylgeranylation, a form of post-translational protein lipid modifi...

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Detalles Bibliográficos
Autores principales: Swan, Gregory, Geng, Jia, Park, Eunchong, Ding, Quanquan, Zhou, John, Walcott, Ciana, Zhang, Junyi J., Huang, Hsin-I, Hammer, Gianna Elena, Wang, Donghai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019753/
https://www.ncbi.nlm.nih.gov/pubmed/33828552
http://dx.doi.org/10.3389/fimmu.2021.641188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019753/
https://www.ncbi.nlm.nih.gov/pubmed/33828552
http://dx.doi.org/10.3389/fimmu.2021.641188

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