Effect of Zebularine on p16INK4a, p14ARF, p15INK4b, and DNA Methyltransferase 1 Gene Expression, Cell Growth Inhibition, and Apoptosis Induction in Human Hepatocellular Carcinoma PLC/PRF5 and Pancreatic Cancer PA-TU-8902 Cell Lines

Tumorigenesis must be understood as a summary of altered genetic and genomic changes resulting in the inactivation of tumor suppressor genes (TSGs). One of the characterizations of epigenetic alterations is DNA methylation. Epigenetic alteration of the p16INK4a, p14ARF, p15INK4b, and DNA methyltrans...

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Detalles Bibliográficos
Autores principales: Sanaei, Masumeh, Kavoosi, Fraidoon, Hosseini, Farzane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019884/
https://www.ncbi.nlm.nih.gov/pubmed/33841535
http://dx.doi.org/10.22037/ijpr.2020.112223.13614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019884/
https://www.ncbi.nlm.nih.gov/pubmed/33841535
http://dx.doi.org/10.22037/ijpr.2020.112223.13614

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