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Comparison the Effect of Metformin and Clomiphene Citrate on Sirtuin3 gene Expression in the Oocytes of Mice with Polycystic Ovary Syndrome

Oxidative stress (OS) is a common biological event in polycystic ovarian syndrome (PCOS), causing oocytes to undergo OS-induced changes. Sirtuin3 (Sirt3) has a critical role in oocyte maturation through the modulation of OS. In the current study, we compared the effects of metformin and clomiphene c...

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Detalles Bibliográficos
Autores principales: Kamalipour, Fatemeh, Jalali, Hanieh, Azarnia, Mahnaz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019885/
https://www.ncbi.nlm.nih.gov/pubmed/33841532
http://dx.doi.org/10.22037/ijpr.2020.113321.14236