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Restoration of NK Cell Cytotoxic Function With Elotuzumab and Daratumumab Promotes Elimination of Circulating Plasma Cells in Patients With SLE

Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease characterized by multiple cellular and molecular dysfunctions of the innate and adaptive immunity. Cytotoxic function of NK cells is compromised in patients with SLE. Herein, we characterized the phenotypic alterations of SLE NK...

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Detalles Bibliográficos
Autores principales: Humbel, Morgane, Bellanger, Florence, Fluder, Natalia, Horisberger, Alice, Suffiotti, Madeleine, Fenwick, Craig, Ribi, Camillo, Comte, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019934/
https://www.ncbi.nlm.nih.gov/pubmed/33828555
http://dx.doi.org/10.3389/fimmu.2021.645478