Inflammatory cytokines in midbrain periaqueductal gray contribute to diabetic induced pain hypersensitivity through phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway

BACKGROUND: Diabetes-related neuropathic pain frequently occurs, and the underpinning mechanism remains elusive. The periaqueductal gray (PAG) exhibits descending inhibitory effects on central pain transmission. The current work aimed to examine whether inflammatory cytokines regulate mechanical all...

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Detalles Bibliográficos
Autores principales: Guo, Mochi, Jiang, Zongming, Chen, Yonghao, Wang, Fei, Wang, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2021
Materias:
Experimental Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019962/
https://www.ncbi.nlm.nih.gov/pubmed/33785669
http://dx.doi.org/10.3344/kjp.2021.34.2.176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019962/
https://www.ncbi.nlm.nih.gov/pubmed/33785669
http://dx.doi.org/10.3344/kjp.2021.34.2.176

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