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Inflammatory cytokines in midbrain periaqueductal gray contribute to diabetic induced pain hypersensitivity through phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway
BACKGROUND: Diabetes-related neuropathic pain frequently occurs, and the underpinning mechanism remains elusive. The periaqueductal gray (PAG) exhibits descending inhibitory effects on central pain transmission. The current work aimed to examine whether inflammatory cytokines regulate mechanical all...
Autores principales: | Guo, Mochi, Jiang, Zongming, Chen, Yonghao, Wang, Fei, Wang, Zhifeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Pain Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019962/ https://www.ncbi.nlm.nih.gov/pubmed/33785669 http://dx.doi.org/10.3344/kjp.2021.34.2.176 |
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