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Proliferation rate and differentiation potential are independent during the transition from neurogenesis to gliogenesis in the mouse embryonic spinal cord

Neural stem cells (NSC) restrict their differentiation potential as the central nervous system develops. Experimental evidence suggests that the mechanisms governing the transition from the neurogenic to the gliogenic phase irreversibly affect the ability of NSC to generate neurons. Cell cycle regul...

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Detalles Bibliográficos
Autores principales: Olivos-Cisneros, Leonora, Ramírez-Santos, Jesús, Gutiérrez-Ospina, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019975/
https://www.ncbi.nlm.nih.gov/pubmed/33842913
http://dx.doi.org/10.1016/j.ibneur.2020.11.004