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Proliferation rate and differentiation potential are independent during the transition from neurogenesis to gliogenesis in the mouse embryonic spinal cord
Neural stem cells (NSC) restrict their differentiation potential as the central nervous system develops. Experimental evidence suggests that the mechanisms governing the transition from the neurogenic to the gliogenic phase irreversibly affect the ability of NSC to generate neurons. Cell cycle regul...
Autores principales: | Olivos-Cisneros, Leonora, Ramírez-Santos, Jesús, Gutiérrez-Ospina, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019975/ https://www.ncbi.nlm.nih.gov/pubmed/33842913 http://dx.doi.org/10.1016/j.ibneur.2020.11.004 |
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