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Analysis of morphological and neurochemical changes in subthalamic nucleus neurons in response to a unilateral 6-OHDA lesion of the substantia nigra in adult rats

BACKGROUND: Subthalamic nucleus (STN) neurons undergo changes in their pattern of activity and morphology during the clinical course of Parkinson’s disease (PD). Striatal dopamine depletion and hyperactivity of neurons in the parafascicular nucleus (Pf) of the intralaminar thalamus are predicted to...

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Detalles Bibliográficos
Autores principales: Sedaghat, Katayoun, Gundlach, Andrew L., Finkelstein, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8019994/
https://www.ncbi.nlm.nih.gov/pubmed/33842916
http://dx.doi.org/10.1016/j.ibneur.2021.01.002