Cargando…

SUR1, newly expressed in astrocytes, mediates neuropathic pain in a mouse model of peripheral nerve injury

BACKGROUND: Neuropathic pain following peripheral nerve injury (PNI) is linked to neuroinflammation in the spinal cord marked by astrocyte activation and upregulation of interleukin 6 (IL-6), chemokine (C-C motif) ligand 2 (CCL2) and chemokine (C-X-C motif) ligand 1 (CXCL1), with inhibition of each...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsymbalyuk, Orest, Gerzanich, Volodymyr, Mumtaz, Aaida, Andhavarapu, Sanketh, Ivanova, Svetlana, Makar, Tapas K, Sansur, Charles A, Keller, Asaf, Nakamura, Yumiko, Bryan, Joseph, Simard, J Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020112/
https://www.ncbi.nlm.nih.gov/pubmed/33788643
http://dx.doi.org/10.1177/17448069211006603