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Melatonin as a therapy in cardiac ischemia-reperfusion injury: Potential mechanisms by which MT2 activation mediates cardioprotection

INTRODUCTION: Previous studies reported the beneficial effects of pretreatment with melatonin on the heart during cardiac ischemia/reperfusion (I/R) injury. However, the effects of melatonin given after cardiac ischemia, as well as its comparative temporal effects are unknown. These include pretreat...

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Detalles Bibliográficos
Autores principales: Singhanat, Kodchanan, Apaijai, Nattayaporn, Jaiwongkam, Thidarat, Kerdphoo, Sasiwan, Chattipakorn, Siriporn C., Chattipakorn, Nipon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020169/
https://www.ncbi.nlm.nih.gov/pubmed/33842003
http://dx.doi.org/10.1016/j.jare.2020.09.007