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Discovery of novel potential KIT inhibitors for the treatment of gastrointestinal stromal tumor
Numerous inhibitors of tyrosine-protein kinase KIT, a receptor tyrosine kinase, have been explored as a viable therapy for the treatment of gastrointestinal stromal tumor (GIST). However, drug resistance due to acquired mutations in KIT makes these drugs almost useless. The present study was designe...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020195/ https://www.ncbi.nlm.nih.gov/pubmed/33851030 http://dx.doi.org/10.1515/biol-2021-0036 |