Discovery of novel potential KIT inhibitors for the treatment of gastrointestinal stromal tumor

Numerous inhibitors of tyrosine-protein kinase KIT, a receptor tyrosine kinase, have been explored as a viable therapy for the treatment of gastrointestinal stromal tumor (GIST). However, drug resistance due to acquired mutations in KIT makes these drugs almost useless. The present study was designe...

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Detalles Bibliográficos
Autores principales: Jiang, Lili, Zhang, Zhongmin, Wang, Zhen, Liu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020195/
https://www.ncbi.nlm.nih.gov/pubmed/33851030
http://dx.doi.org/10.1515/biol-2021-0036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020195/
https://www.ncbi.nlm.nih.gov/pubmed/33851030
http://dx.doi.org/10.1515/biol-2021-0036

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