Triptolide inhibits JAK2/STAT3 signaling and induces lethal autophagy through ROS generation in cisplatin-resistant SKOV3/DDP ovarian cancer cells

Advanced and recurrent ovarian cancer has a poor prognosis and is frequently resistant to numerous therapeutics; thus, safe and effective drugs are needed to combat this disease. Previous studies have demonstrated that triptolide (TPL) exhibits anticancer and sensitization effects against cisplatin...

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Detalles Bibliográficos
Autores principales: Zhong, Yanying, Le, Fuyin, Cheng, Jiao, Luo, Chen, Zhang, Xiali, Wu, Xingwu, Xu, Fang, Zuo, Qi, Tan, Buzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020210/
https://www.ncbi.nlm.nih.gov/pubmed/33760192
http://dx.doi.org/10.3892/or.2021.8020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020210/
https://www.ncbi.nlm.nih.gov/pubmed/33760192
http://dx.doi.org/10.3892/or.2021.8020

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