Osthole Attenuates Macrophage Activation in Experimental Asthma by Inhibitingthe NF-ĸB/MIF Signaling Pathway

Inhibition of activated macrophages is an alternative therapeutic strategy for asthma. We investigated whether a coumarin compound, osthole, isolated from Cnidium monnieri (L.) Cuss, alleviated macrophage activation in vivo and in vitro. Osthole could reduce expression of a marker of activated macro...

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Detalles Bibliográficos
Autores principales: Li, Ruyi, Song, Peng, Tang, Guofang, Wei, Jianghong, Rao, Lizong, Ma, Libing, Jiang, Ming, Huang, Jianwei, Xu, Qing, Wu, Jingjie, Lv, Qian, Yao, Dong, Xiao, Bo, Huang, Haiming, Lei, Liping, Feng, Juntao, Mo, Biwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020258/
https://www.ncbi.nlm.nih.gov/pubmed/33828480
http://dx.doi.org/10.3389/fphar.2021.572463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020258/
https://www.ncbi.nlm.nih.gov/pubmed/33828480
http://dx.doi.org/10.3389/fphar.2021.572463

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