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Novel reporter mouse models useful for evaluating in vivo gene editing and for optimization of methods of delivering genome editing tools
The clustered regularly interspersed palindromic repeats (CRISPR) system is a powerful genome-editing tool to modify genomes, virtually in any species. The CRISPR tool has now been utilized in many areas of medical research, including gene therapy. Although several proof-of-concept studies show the...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020343/ https://www.ncbi.nlm.nih.gov/pubmed/33850636 http://dx.doi.org/10.1016/j.omtn.2021.03.003 |