Physiologically-based pharmacokinetic model for clozapine in Korean patients with schizophrenia

Clozapine has been used as a treatment of schizophrenia. Despite its large interindividual variability, few reports addressed the physiologically-based pharmacokinetic modeling and simulation (PBPK M&S) of clozapine in patients. This study aimed to develop a PBPK M&S of clozapine in Korean p...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Joomi, Kim, Min-Gul, Jeong, Hyeon-Cheol, Shin, Kwang-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020364/
https://www.ncbi.nlm.nih.gov/pubmed/33854999
http://dx.doi.org/10.12793/tcp.2021.29.e3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020364/
https://www.ncbi.nlm.nih.gov/pubmed/33854999
http://dx.doi.org/10.12793/tcp.2021.29.e3

Ejemplares similares