Antinociceptive Effect of Lodenafil Carbonate in Rodent Models of Inflammatory Pain and Spinal Nerve Ligation-Induced Neuropathic Pain

INTRODUCTION: New therapeutic alternatives for pain relief include the use of phosphodiesterase-5 (PDE5) inhibitors, which could prevent the transmission of painful stimuli by neuron hyperpolarization via nitric oxide (NO)/cyclic 3ʹ,5ʹ-guanosine monophosphate (cGMP) pathway. The present work investi...

Descripción completa

Detalles Bibliográficos
Autores principales: Vieira, Marcio Carneiro, Monte, Fernanda Bezerra de Mello, Eduardo Dematte, Bruno, Montagnoli, Tadeu Lima, Montes, Guilherme Carneiro, da Silva, Jaqueline Soares, Mendez-Otero, Rosalia, Trachez, Margarete Manhães, Sudo, Roberto Takashi, Zapata-Sudo, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020462/
https://www.ncbi.nlm.nih.gov/pubmed/33833563
http://dx.doi.org/10.2147/JPR.S295265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020462/
https://www.ncbi.nlm.nih.gov/pubmed/33833563
http://dx.doi.org/10.2147/JPR.S295265

Ejemplares similares