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Dexmedetomidine Attenuates Ischemia/Reperfusion-Induced Myocardial Inflammation and Apoptosis Through Inhibiting Endoplasmic Reticulum Stress Signaling

BACKGROUND: Endoplasmic reticulum stress (ERS)-mediated myocardial inflammation and apoptosis plays an important role in myocardial ischemia/reperfusion (I/R) injury. Dexmedetomidine has been used clinically with sedative, analgesic, and anti-inflammatory properties. This study aimed to determine th...

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Detalles Bibliográficos
Autores principales: Yang, Yu-fan, Wang, Hui, Song, Nan, Jiang, Ya-hui, Zhang, Jun, Meng, Xiao-wen, Feng, Xiao-mei, Liu, Hong, Peng, Ke, Ji, Fu-hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020464/
https://www.ncbi.nlm.nih.gov/pubmed/33833544
http://dx.doi.org/10.2147/JIR.S292263