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Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins

Numerous proteins that have hydrophobic transmembrane domains (TMDs) traverse the cytosol and posttranslationally insert into cellular membranes. It is unclear how these hydrophobic membrane proteins evade recognition by the cytosolic protein quality control (PQC), which typically recognizes exposed...

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Detalles Bibliográficos
Autores principales: Culver, Jacob A., Mariappan, Malaiyalam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020466/
https://www.ncbi.nlm.nih.gov/pubmed/33792613
http://dx.doi.org/10.1083/jcb.202004086