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Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins
Numerous proteins that have hydrophobic transmembrane domains (TMDs) traverse the cytosol and posttranslationally insert into cellular membranes. It is unclear how these hydrophobic membrane proteins evade recognition by the cytosolic protein quality control (PQC), which typically recognizes exposed...
Autores principales: | Culver, Jacob A., Mariappan, Malaiyalam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020466/ https://www.ncbi.nlm.nih.gov/pubmed/33792613 http://dx.doi.org/10.1083/jcb.202004086 |
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