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The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19

Complement system plays a dual role; physiological as well as pathophysiological. While physiological role protects the host, pathophysiological role can substantially harm the host, by triggering several hyper-inflammatory pathways, referred as “hypercytokinaemia”. Emerging clinical evidence sugges...

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Detalles Bibliográficos
Autores principales: Das, Aurosikha, Rana, Soumendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020607/
https://www.ncbi.nlm.nih.gov/pubmed/33845430
http://dx.doi.org/10.1016/j.compbiolchem.2021.107482