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Restriction of food intake by PPP1R17-expressing neurons in the DMH

Leptin-deficient ob/ob mice eat voraciously, and their food intake is markedly reduced by leptin treatment. In order to identify potentially novel sites of leptin action, we used PhosphoTRAP to molecularly profile leptin-responsive neurons in the hypothalamus and brainstem. In addition to identifyin...

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Detalles Bibliográficos
Autores principales: Caglar, Caner, Friedman, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020659/
https://www.ncbi.nlm.nih.gov/pubmed/33753517
http://dx.doi.org/10.1073/pnas.2100194118