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The number of catalytic cycles in an enzyme’s lifetime and why it matters to metabolic engineering

Metabolic engineering uses enzymes as parts to build biosystems for specified tasks. Although a part’s working life and failure modes are key engineering performance indicators, this is not yet so in metabolic engineering because it is not known how long enzymes remain functional in vivo or whether...

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Detalles Bibliográficos
Autores principales: Hanson, Andrew D., McCarty, Donald R., Henry, Christopher S., Xian, Xiaochen, Joshi, Jaya, Patterson, Jenelle A., García-García, Jorge D., Fleischmann, Scott D., Tivendale, Nathan D., Millar, A. Harvey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020674/
https://www.ncbi.nlm.nih.gov/pubmed/33753504
http://dx.doi.org/10.1073/pnas.2023348118