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Human Pluripotent Stem Cells to Model Islet Defects in Diabetes

Diabetes mellitus is characterized by elevated levels of blood glucose and is ultimately caused by insufficient insulin production from pancreatic beta cells. Different research models have been utilized to unravel the molecular mechanisms leading to the onset of diabetes. The generation of pancreat...

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Detalles Bibliográficos
Autores principales: Balboa, Diego, Iworima, Diepiriye G., Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8020750/
https://www.ncbi.nlm.nih.gov/pubmed/33828531
http://dx.doi.org/10.3389/fendo.2021.642152